DGL by Bioclinic Naturals supports the stomach lining by stimulating mucous formation and secretion, offering almost immediate occasional relief for stomach and digestive tract discomfort. It is specially processed to have glycyrrhizin removed to avoid potential side effects such as elevated blood pressure. The chewable delivery system is preferred because saliva enhances the effect of DGL’s natural compounds.

Deglycyrrhizinated licorice, or DGL, has been used clinically for decades, primarily for the treatment of peptic ulcers. Licorice has been shown to inhibit several inflammatory enzymes, including both cyclooxygenase-2 (COX-2) and 5-lipoxygenase (5-LOX), decreasing the production of several potent inflammatory compounds, including prostaglandin E2, thromboxane B2, and leukotriene B4. Importantly, this inhibition is not due to glycyrrhizic acid, the component of licorice which has been removed in DGL, and which is associated with mineralocorticoid excess and hypertension.

Another component of licorice, glabridin, has been shown to prevent lipopolysaccharide (LPS) induced production of inflammatory compounds, including nitric oxide and interleukin-1 beta, whereas glycyrrhizic acid has no effect.

Clinically, DGL has been shown to have comparable efficacy to cimetidine for both the healing and prevention of ulcer recurrences.

Additionally, extracts of licorice have been shown to inhibit the adhesion of H. pylori to gastric mucosa, as well as the growth of antibiotic resistant strains, suggesting multiple mechanisms of action for its anti-ulcer benefit.

The use of chewable tablets appears necessary for DGL’s efficacy, as it allows for distribution and absorption by the gastric mucosa.

DGL Benefits:
• DGL chewable tablets is the form associated with the greatest clinical efficacy, as it allows for licorice to be released in the stomach and dispersed/absorbed by the gastric mucosa
• Provides 400 mg DGL per tablet, the clinically effective dosage
• Deglycyrrhizination prevents adverse effects associated with licorice consumption
• Pleasant tasting tablets for better compliance

DGL Ingredients in 1 tablet:
Deglycyrrhizinated Licorice 10:1 Extract (Glycyrrhiza glabra) (root) 400 mg. Providing 4,000 mg crude herb licorice. Other ingredients: Xylitol, microcrystalline cellulose, aniseed, stearic acid, vegetable grade magnesium stearate (lubricant), silica and Stevia rebaudiana leaf.

This product does not contain artificial colors, preservatives, or sweeteners; no dairy, starch, sugar, wheat, gluten, yeast, soy, corn, egg, fish, shellfish, animal products, salt, tree nuts, or GMOs. Suitable for vegetarians/vegans.

Suggested Use:
Chew 1 tablet 20 minutes before each meal or as directed by your healthcare practitioner. Consult your healthcare practitioner for use beyond 16 weeks.

Consult your healthcare practitioner prior to use if you are pregnant, nursing, have hypertension, congestive heart failure or hypokalemia. Consult your healthcare practitioner if you experience persistent stomach or gastrointestinal upset.

Caution: Licorice influences the activity of several cytochrome enzymes, and reduces warfarin activity in animal models, likely due to glycyrrhizic acid activity. Thus DGL use should be carefully monitored by your healthcare practitioner.

Keep out of reach of children.